Hi,
The genetic disorder called Klinfelters may or may not be related to some psychiatric disorders such as in
your husband's case. I think any ways your husband is on the right course of treatment.
However, if the benefit is not complete, you may go back to the doctor treating him and get him re-examined
and the drugs re-prescribed, such that a trial to get more relief is done.
On the other hand, you must realise that your husband may be undergoing severe bout at present and with time
he may improve considerably.
Let me know if you any further queries